聚乙二醇修飾參考文獻

來源：作者：人氣：-發表時間：2014-12-08 15:09:00【大中小】

聚乙二醇修飾參考文獻

活性聚乙二醇試劑是用來衍生、官能團化、共軛或交聯一些列底物分子、顆粒和表面。以下所列是一部分經過挑選運用PEG產品成功進行聚乙二醇修飾的文獻案例。

I. 生物質的聚乙二醇修飾 – 蛋白質、抗體、肽、核酸
II. 納米粒子、表面、芯片、膜的聚乙二醇修飾
III. Biotin的聚乙二醇修飾和生物素化
IV. 聚乙二醇交聯劑 - 藥物傳遞，分子成像，生物物理
V. 聚乙二醇水凝膠 - 再生醫學，組織工程，藥物傳遞
VI. 自組裝 - 聚乙二醇化脂質體，膠束，單層平面
VII. 小分子聚乙二醇化及其他

mPEG-Maleimide(蛋白質巰基的PEG修飾) - Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel, Biochemistry, 2012, 51(31), pp 6195–6206, Text.

mPEG-Maleimide(蛋白質巰基的PEG修飾) - The holin of bacteriophage lambda forms rings with large diameter, Molecular Microbiology, 09/2008; 69(4):784-793, Text.

mPEG-Maleimide(蛋白質巰基的PEG修飾) - In vitro folding of KvAP, a voltage gated K+ channel, Biochemistry. 2011 6; 50(48): 10442–10450, Text.

mPEG-MAL(半胱氨酸肽巰基的PEG修飾) - Structure of the lethal phage pinhole, Proc Natl Acad Sci USA. 2009;106(45):18966-71, Text.

mPEG-MAL(蛋白質巰基的PEG修飾) - A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells, Cell, Volume 157, Issue 7, 19 June 2014, Pages 1644–1656, Text.

mPEG-NHS(肽氨基的PEG修飾) - High Efficiency Diffusion Molecular Retention Tumor Targeting. PLoS ONE 8(3): e58290, Text, Experimental details in SI.

mPEG-NHS(用于基因傳遞的PEG修飾聚合物) - BSA Nanoparticles for siRNA Delivery: Coating Effects on Nanoparticle Properties, Plasma Protein Adsorption, and In Vitro siRNA Delivery, International Journal of Biomaterials, Volume 2012, Article ID 584060, 10 pages, Text.

mPEG-SCM(賴氨酸肽氨基的PEG修飾) - PEG-Like Nanoprobes: Multimodal, Pharmacokinetically and Optically Tunable Nanomaterials, PLoS ONE 9(4): e95406, Text.

mPEG-SCM(蛋白質氨基的PEG修飾) - PEGylation of lysine residues improves the proteolytic stability of fibronectin while retaining biological activity, Biotechnol. J. 2014, 9, Text.

mPEG-Alkyne(蛋白質的點擊化學PEG修飾) - Identification and Origin of N-Linked b-D-NAcetylglucosamine Monosaccharide Modifications on Arabidopsis Proteins. Plant Physiology, 2013, 161: 455–464, Text.

mPEG-Alkyne(蛋白質的點擊化學PEG修飾) - Visualization of O‐GlcNAc Glycosylation Stoichiometry and Dynamics Using Resolvable Poly(ethylene glycol) Mass Tags, Current Protocols in Chemical Biology, 5:281–302, Text.

mPEG-Epoxide(多糖的羥基PEG修飾) - Surface Grafting of Cellulose Nanocrystals with Poly(ethylene oxide) in Aqueous Media, Langmuir 2010, 26(16), 13450–13456, Text.

mPEG-Aminooxy(糖的羰基PEG修飾) - Visualization of O‐GlcNAc Glycosylation Stoichiometry and Dynamics Using Resolvable Poly(ethylene glycol) Mass Tags, Current Protocols in Chemical Biology, 5:281–302, Text.

Acrylate-PEG-Acrylate(siRNA的巰基PEG修飾) - Methods and Compositions for Improved Therapeutic Effects with siRNA, Patent US20080311040 A1, Text.

4-Arm PEG-Amine(siRNA遞送載體) - Multi-armed cationic cyclodextrin: poly(ethylene glycol) polyrotaxanes as efficient gene silencing vectors, Integr. Biol., 2013,5, 115-121, Text.

納米粒子、表面、芯片、膜的聚乙二醇修飾

mPEG-Thiol(金納米棒的巰基PEG修飾) - Spatiotemporal Temperature Distribution and Cancer Cell Death in Response to Extracellular Hyperthermia Induced by Gold Nanorods, ACS Nano, 2010 May 25; 4(5): 2892–2900, Text.

mPEG-SH(金納米顆粒表面的PEG修飾) - On Sensitivity of Molecular Specific Photoacoustic Imaging Using Plasmonic Gold Nanoparticles, Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6338-40, Text.

mPEG-SH(表面PEG修飾) - Gold nanorod mediated plasmonic photothermal therapy: A tool to enhance macromolecular delivery, Int J Pharm. 2011 August 30; 415(1-2): 315–318, Text.

mPEG-SH(金納米棒表面的PEG修飾) - Intravascular photoacoustic imaging of exogenously labeled atherosclerotic plaque through luminal blood , J. Biomed. Opt. 17(10), 106016(Oct 17, 2012), Text.

mPEG-SH(金納米棒表面的PEG修飾) - Conjugation of antibodies to gold nanorods through Fc portion: synthesis and molecular specific imaging, Bioconjug Chem. 2013 June 19; 24(6): 878–888, Text.

mPEG-SH(金屬納米顆粒表面的PEG修飾) - Plasmon-Resonant Gold Nanoparticles with Variable Morphology as Optical Labels and Drug Carriers for Cytological Research, Proc. of SPIE-OSA/ Vol. 8801 880102-2, Text.

mPEG-SH(納米棒表面的PEG修飾) - Gold nanorod-mediated hyperthermia enhances the efficacy of HPMA copolymer-90Y conjugates in treatment of prostate tumors, Nuclear Medicine and Biology 41(2014) 282–289, Text.

mPEG-SH(納米顆粒表面的PEG修飾) - Detecting protein adsorption and binding using magnetic nanoparticle probes, Sensors and Actuators B 160(2011) 650– 655, Text.

HS-PEG-COOH(金屬納米顆粒表面的PEG修飾) - Capping and in vivo toxicity studies of gold nanoparticles. Adv. Nat. Sci.: Nanosci. Nanotechnol. 3(2012) 015002(5pp), Text.

HS-PEG-NH2(金屬納米顆粒表面的PEG修飾) - Gold Nanorods: Controlling Their Surface Chemistry and Complete Detoxification by a Two-Step Place Exchange. Angewandte Chemie 2013, 125(7): 1988-1992. Text, experimental details in SI.

mPEG-Amine(納米顆粒的羧基PEG修飾) - Upconverting Luminescent Nanomaterials: Application to In Vivo Bioimaging, Chem Commun(Camb). 2009 Jul 28;(28):4188-90, Text, experimental details in SI.

mPEG-Amine(納米顆粒的羧基PEG修飾) - Design and demonstration of a small-animal upconversion imager, Opt Express. 2008 December 22; 16(26): 21731–21737, Text.

mPEG-Amine(羧基PEG修飾) - Fluorescence Single Particle Tracking for the Characterization of Submicron Protein Aggregates in Biological Fluids and Complex Formulations, Pharm Res(2011) 28:1112–1120, Text.

mPEG-Amine(羧基PEG修飾) - Characterization of hydrogel microstructure using laser tweezers particle tracking and confocal reflection imaging, J Phys Condens Matter. 2010; 22(19): 194121, Text.

mPEG-Amine(納米顆粒的羧基PEG修飾) - Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues, Mol Pharm. 2013 June 3; 10(6): 2176–2182, Text.

mPEG-Amine(納米顆粒的羧基PEG修飾) - Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo, J Control Release. 2013 April 10; 167(1): 76–84, Text.

mPEG-Amine(納米顆粒的羧基PEG修飾) - Nanoparticle diffusion in respiratory mucus from humans without lung disease, Biomaterials. 2013 April ; 34(13): 3439–3446, Text.

mPEG-Amine(羧基取代納米顆粒的PEG修飾) - Immobilization of Pseudorabies Virus in Porcine Tracheal Respiratory Mucus Revealed by Single Particle Tracking, PLoS ONE 7(12): e51054, Text.

mPEG-Acid(氨基取代納米顆粒的PEG修飾) - Interfacial polymer phase segregation and self-assembly of square colloidal crystals, Soft Matter, 2012, 8, 6684, Text.

mPEG-Silane(納米顆粒表面的PEG修飾) - Measurement of enzyme kinetics and inhibitor constants using enthalpy arrays, Anal Biochem. 2009 May 15; 388(2): 204–212, Text.

mPEG-Silane(玻璃表面的PEG修飾) - Rapid mixing of sub-microliter drops by magnetic micro-stirring, Lab Chip. 2011 October 7; 11(19): 3313–3319, Text.

mPEG-Silane(硅表面PEG修飾) - Fluorinated Silicon Surfaces under Mixed Surfactants: Resistance to Nonspecific Protein Adsorption for Biosensing, Langmuir. 2009 Nov 3;25(21):12404-7, Text.

mPEG-Silane(納米顆粒的羥基PEG修飾) - Biocompatibility, MR imaging and targeted drug delivery of a rattle-type magnetic mesoporous silica nanosphere system conjugated with PEG and cancer-cell-specific ligands, J. Mater. Chem., 2011, 21, 3037, Text.

mPEG-Silane(玻璃表面的PEG修飾) - MAP65/Ase1 promote microtubule flexibility, Mol. Biol. Cell, June 15, 2013 vol. 24 no. 12 1964-1973, Text.

mPEG-Silane:(硅表面PEG修飾) - Micropatterning neuronal networks, Analyst, 2014, 139, 3256-3264, Text.

mPEG-NHS(芯片氨基的PEG修飾) - Fabricating Nanoscale DNA Patterns with Gold Nanowires, Anal Chem. 2010 April 15; 82(8): 3365–3370, Text.

mPEG-SG(氨基取代表面的PEG修飾) - Experimental and Numerical Studies of Tethered DNA Shear Dynamics in the Flow-Gradient Plane, Macromolecules, 2009, 42(22), pp 9170–9182, Text.

mPEG-Azide(膜的點擊化學PEG修飾) - Effect of End Groups and Grafting on the CO2 Separation Performance of Poly(ethylene glycol) Based Membranes , Macromolecules, 2011, 44(19), pp 7727–7736, Text.

mPEG-Azide(納米顆粒的點擊化學PEG修飾) - Biomimetic Mussel Adhesive Inspired Clickable Anchors Applied to the Functionalization of Fe3O4 Nanoparticles, Macromol. Rapid Commun. 2010, 31, 1608–1615, Text.

mPEG-Aldehyde(膠束的可逆肼PEG修飾) - The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabineloaded micelles on drug resistance caused by RRM1 overexpression, Biomaterials. 2013 March; 34(9): 2327–2339, Text.

生物素的聚乙二醇修飾和生物素化

Biotin-PEG-NHS(生物素化和芯片氨基PEG修飾) - Multi-modal particle manipulator to enhance bead-based bioassays, Ultrasonics. 2010 Feb;50(2):235-9, Text.

Biotin-PEG-NHS(氨基取代微球的生物素化) - Flexible Acoustic Particle Manipulation Device with Integrated Optical Waveguide for Enhanced Microbead Assays, Anal Sci. 2009; 25(2):285-91, Text.

Biotin-PEG-SCM(氨基取代表面的生物素化) - Experimental and Numerical Studies of Tethered DNA Shear Dynamics in the Flow-Gradient Plane, Macromolecules, 2009, 42(22), pp 9170–9182, Text.

Biotin-PEG-SCM(核酸氨基的PEG修飾) - Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene Silencing, J. Am. Chem. Soc., 2012, 134(17), pp 7423–7430, Text.

Biotin-PEG-Silane(羥基取代表面的生物素化) - MAP65/Ase1 promote microtubule flexibility, Mol. Biol. Cell, June 15, 2013 vol. 24 no. 12 1964-1973, Text.

聚乙二醇交聯劑 - 藥物傳遞，分子成像，生物物理

OPSS-PEG-NHS(抗體(胺基PEG修飾) 與納米顆粒(巰基PEG修飾)的交聯 ) - Silica-gold nanoshells as potential intraoperative molecular probes for HER2-overexpression in ex vivo breast tissue using near-infrared reflectance confocal microscopy, Breast Cancer Res Treat, 2010; 120(3):547-55, Text.

OPSS-PEG-NHS(抗體(胺基PEG修飾) 與納米顆粒(巰基PEG修飾)的交聯) - Evaluation of Immunotargeted Gold Nanoshells as Rapid Diagnostic Imaging Agents for HER2-Overexpressing Breast Cancer Cells: A Time-based Analysis, Nanobiotechnology, vol. 4, no. 1–4, pp. 1–8, 2008, Text.

OPSS-PEG-NHS(抗體(胺基PEG修飾)與納米顆粒(巰基PEG修飾)的交聯) - Enhanced multi-spectral imaging of live breast cancer cells using immunotargeted gold nanoshells and two-photon excitation microscopy, Nanotechnology 19(2008) 315102, Text.

OPSS-PEG-NHS(蛋白質(胺基PEG修飾)與納米顆粒(巰基PEG修飾)的交聯) - Detection of chronic lymphocytic leukemia cell surface markers using surface enhanced Raman scattering gold nanoparticles, Cancer Lett. 2010, 1;292(1):91-7, Text.

OPSS-PEG-NHS(肽(胺基PEG修飾)與納米顆粒(巰基PEG修飾)的交聯) - Biological evaluation of RGDfK-gold nanorod conjugates for prostate cancer treatment. Journal of Drug Targeting, 2011; 19(10): 915–924, Text.

OPSS-PEG-NHS(抗體(胺基PEG修飾)與納米顆粒(巰基PEG修飾)的交聯) - Controlled release of Rituximab from gold nanoparticles for phototherapy of malignant cells, Journal of Controlled Release, 162(2012) 303–309, Text.

OPSS-PEG-NHS(蛋白質(胺基PEG修飾)與納米顆粒(巰基PEG修飾)的交聯) - Gold nanorods for target selective SPECT/CT imaging and photothermal therapy in vivo. Quant Imaging Med Surg, 2012;2:1-11, Text,

OPSS-PEG-NHS(蛋白質(胺基PEG修飾)與納米顆粒(巰基PEG修飾)的交聯) - Gold nanostars: surfactant-free synthesis, 3D modelling, and two-photon photoluminescence imaging, Nanotechnology. 2012 February 24; 23(7): 075102, Text,

OPSS-PEG-NHS(抗體(胺基PEG修飾) 與納米顆粒(巰基PEG修飾)的交聯) - Multiplexed Dot Immunoassay Using Ag Nanocubes, Au/Ag Alloy Nanoparticles, and Au/Ag Nanocages, Nano Res. 2012, 5(2): 124–134, Text,

OPSS-PEG-NHS(肽(胺基PEG修飾)與表面(巰基PEG修飾)的交聯) - Peptide-Surface Adsorption Free Energy Comparing Solution Conditions Ranging from Low-to-Medium Salt Concentrations, Chemphyschem. 2012, 13(17): 3782–3785, Text,

OPSS-PEG-NHS(siRNA和寡核苷酸(巰基PEG修飾) 單糖和多糖(胺基PEG修飾)的交聯) - Targeted Delivery of siRNA to Hepatocytes and Hepatic Stellate Cells by Bioconjugation, Bioconjugate Chem. 2010, 21, 2119–2127, Text,

MAL-PEG-NHS( 肽(巰基PEG修飾) 與聚合物(胺基PEG修飾)的交聯) - Virus-Inspired Approach to Nonviral Gene Delivery Vehicles, Biomacromolecules. 2009, 10;10(8):2189-93, Text.

MAL-PEG-NHS(蛋白質(巰基PEG修飾)與小分子(胺基PEG修飾)的交聯) - Synthesis and characterization of scVEGF-PEG-[68Ga]NOTA and scVEGF-PEG-[68Ga]DOTA PET tracers, J. Label Compd. Radiopharm, 2011, 54 685–692, Text.

MAL-PEG-SCM(蛋白質(胺基PEG修飾)與巰基取代表面的交聯) - Structure and Biosynthesis of Two Exopolysaccharides Produced by Lactobacillus johnsonii FI9785, J. Biol. Chem. 2013, 288:31938-31951, Text.

MAL-PEG-SCM(肽(胺基PEG修飾)與巰基取代納米顆粒的交聯) - Cancer-Targeted Optical Imaging with Fluorescent Zinc Oxide Nanowires, Nano Lett. 2011 September 14; 11(9): 3744–3750, Text.

MAL-PEG-SCM(肽(胺基PEG修飾)與巰基取代納米顆粒的交聯) - Evolution of zinc oxide nanostructures through kinetics control, J. Mater. Chem., 2011, 21, 9000-9008, Text.

MAL-PEG-SCM(肽(胺基PEG修飾)與巰基取代膽固醇的交聯) - Design of a Modular Tetrameric Scaffold for the Synthesis of Membrane-Localized d-Peptide Inhibitors of HIV-1 Entry, Bioconjugate Chem., 2012, 23(6), pp 1252–1258, Text.

MAL-PEG-SCM(肽(巰基PEG修飾)納米顆粒的交聯) - Methylene blue covalently loaded polyacrylamide nanoparticles for enhanced tumor-targeted photodynamic therapy, Photochem. Photobiol. Sci., 2011, 10, 832-841, Text.

MAL-PEG-SCM(抗體(巰基PEG修飾) 與石墨烯的交聯) - Tumor Vasculature Targeting and Imaging in Living Mice with Reduced Graphene Oxide, Biomaterials. 2013 April ; 34(12): 3002–3009, Text.

MAL-PEG-SCM(抗體(巰基PEG修飾) 與石墨烯的交聯) - In Vivo Targeting and Positron Emission Tomography Imaging of Tumor Vasculature with 66Ga-Labeled Nano-Graphene, Biomaterials. 2012 June; 33(16): 4147–4156, Text.

MAL-PEG-SCM(蛋白質與肽的交聯) - Novel engineered targeted interferon-gamma blocks hepatic fibrogenesis in mice, Hepatology, 54: 586–596, Text.

MAL-PEG-Amine(抗體(特殊位點巰基PEG修飾) 與樹狀聚合物(羧基PEG修飾)的交聯) - Transbuccal Delivery of CNS Therapeutic Nanoparticles: Synthesis, Characterization, and In Vitro Permeation Studies, ACS Chem. Neurosci., 2011, 2(11), pp 676–683, Text.

MAL-PEG-NH2( siRNA(巰基PEG修飾) 與化療藥物(羧基PEG修飾)的交聯) - Methods and Compositions for Improved Therapeutic Effects with siRNA, Patent US20080311040 A1, Text.

Hydrazide-PEG-OPSS(抗體(羰基PEG修飾)與納米顆粒(巰基PEG修飾)的交聯) - Multiwavelength Photoacoustic Imaging and Plasmon Resonance Coupling of Gold Nanoparticles for Selective Detection of Cancer, Nano Lett. 2009 August ; 9(8): 2825–283, Text.

Hydrazide-PEG-OPSS(抗體(特殊位點的羰基PEG修飾)與納米顆粒(巰基PEG修飾)的交聯) - EGFR-Targeted Hybrid Plasmonic Magnetic Nanoparticles Synergistically Induce Autophagy and Apoptosis in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2011, 6(11): e25507, Text.

HS-PEG-COOH(蛋白質(胺基PEG修飾)與金芯片的交聯) - Single-Molecule Force Spectroscopy of the Aplysia Cell Adhesion Molecule Reveals Two Homophilic Bonds. Biophysical Journal 2012; 103: 649–657, Text.

HS-PEG-COOH(金納米粒子的交聯抗體) - The Effect of Nanoparticle Size on Cellular Binding Probability, Journal of Atomic, Molecular, and Optical Physics. 2012(2012), Article ID 404536, 7 pages, Text.

HS-PEG-COOH(蛋白質與金納米棒的交聯) - A new method for cancer detection based on diffusion reflection measurements of targeted gold nanorods, Int J Nanomedicine. 2012;7: 449–455, Text.

HS-PEG-COOH(金納米粒子的交聯抗體) - Targeted gold nanoparticles enable molecular CT imaging of cancer: an in vivo study, Int J Nanomedicine. 2011; 6: 2859–2864, Text.

HS-PEG-COOH(金納米粒子的交聯抗體) - Towards real-time detection of tumor margins using photothermal imaging of immune-targeted gold nanoparticles, Int J Nanomedicine. 2012; 7: 4707–4713, Text.

HS-PEG-COOH(蛋白質與金芯片的交聯) - Surface-modified microprojection arrays for intradermal biomarker capture, with low non-specific protein binding, Lab Chip, 2010, 10, 2655–2658, Text.

Thiol-PEG-Acid(酶與金表面交聯) - High-Resolution Single-Molecule Recognition Imaging of the Molecular Details of Ricin−Aptamer Interaction, J. Phys. Chem. B 2012, 116, 5316−5322, Text.

Thiol-PEG-Acid(蛋白質與納米顆粒交聯) - Transport of nanoparticles through the blood–brain barrier for imaging and therapeutic applications, Nanoscale, 2014, 6, 2146, Text.

Thiol-PEG-Acid(金納米粒子的交聯抗體) - New optical method for enhanced detection of colon cancer by capsule endoscopy, Nanoscale, 2013, 5, 9806, Text.

Thiol-PEG-Amine(納米粒子的交聯抗體) - Orthogonal Amplification of Nanoparticles for Improved Diagnostic Sensing, ACS Nano, 2012, 6(4), pp 3506–3513, Text.

Acrylate-PEG-SCM(蛋白質共軛(胺基PEG修飾)與PEG水凝膠交聯) - Bioartificial matrices for therapeutic vascularization, Proc Natl Acad Sci USA. 2010; 107(8): 3323–3328, Text.

Acrylate-PEG-NHS(蛋白質與PEG水凝膠交聯) - Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration, Biomaterials, 2013(34): 7381-7388, Text.

Acrylate-PEG-NHS(蛋白質與PEG水凝膠交聯) - Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration, Acta Biomaterialia 10(2014) 1102–1111, Text.

4-Arm PEG-Acrylate(巰基取代siRNA交聯) - Methods and Compositions for Improved Therapeutic Effects with siRNA, Patent US20080311040 A1, Text.

NHS-PEG-NHS(核苷與硅表面交聯) - Efficient self-assembly of DNA-functionalized fluorophores and gold nanoparticles with DNA functionalized silicon surfaces: the effect of oligomer spacers. Nucleic Acids Research, 2013, 1–12, Text.

NHS-PEG-NHS(Crosslinking siRNA(胺基PEG修飾) to Antibody(胺基PEG修飾)交聯) - Methods and Compositions for Improved Therapeutic Effects with siRNA, Patent US20080311040 A1, Text.

聚乙二醇水凝膠 - 再生醫學，組織工程，藥物傳遞

Thiol-PEG-Thiol(PEG水凝膠) - Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration, Biomaterials, 2013(34): 7381-7388, Text.

Maleimide-PEG-Maleimide(交聯蛋白質和水凝膠) - Controlling topological entanglement in engineered protein hydrogels with a variety of thiol coupling chemistries, Front. Chem. 2:23. doi: 10.3389/fchem.2014.00023, Text.

mPEG-Acrylate(丙烯酸聚乙二醇修飾) - Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene , J. Am. Chem. Soc., 2012, 134(17), pp 7423–7430, Text.

Acrylate-PEG-Acrylate(PEG水凝膠) - Bioartificial matrices for therapeutic vascularization, Proc Natl Acad Sci USA. 2010; 107(8): 3323–3328, Text.

Acrylate-PEG-Acrylate(PEG水凝膠) - Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene Silencing, J. Am. Chem. Soc., 2012, 134(17), pp 7423–7430, Text.

Acrylate-PEG-NHS(PEG-PCL 水凝膠和蛋白質共軛) - Shape Memory RGD-Containing Networks: Synthesis, Characterization, and Application in Cell Culture, Macromol. Symp. 2011, 309/310, 162–172, Text.

Azide-PEG-Azide(點擊化學和PEG-透明質酸水凝膠) - Age-Related Dysfunction in Mechanotransduction Impairs Differentiation of Human Mammary Epithelial Progenitors, Cell Reports 7, 1926–1939, June 26, 2014, Text.

4-Arm PEG-Acrylate(丙烯酸聚乙二醇修飾和水凝膠) - Hydrogel network design using multifunctional macromers to coordinate tissue maturation in ovarian follicle culture, Biomaterials, Volume 32, Issue 10, April 2011, Pages 2524–2531, Text.

4-Arm PEG-SH(PEG水凝膠) - Thiolated hyaluronan-based hydrogels crosslinked using oxidized glutathione: An injectable matrix designed for ophthalmic applications, Acta Biomaterialia 10(2014) 94–103, Text.

4-Arm PEG Alkyne(點擊化學) - Biodegradable poly(ethylene glycol)–peptide hydrogels with well-defined structure and properties for cell delivery, Biomaterials. 2009 Mar;30(8):1453-61, Text.

4-Arm PEG-Azide and 4-Arm PEG-Alkyne(可點擊化學的PEG水凝膠) - Ultralow Protein Adsorbing Coatings from Clickable PEG Nanogel Solutions: Benefits of Attachment under Salt-Induced Phase Separation Conditions and Comparison with PEG/Albumin Nanogel Coatings. Langmuir 2013, 29, 4128−4139, Text.

4-Arm PEG-Alkyne(點擊化學PEG水凝膠) - Photoinitiated Alkyne−Azide Click and Radical Cross-Linking Reactions for the Patterning of PEG Hydrogels, Biomacromolecules 2012, 13, 889−895, Text.

4-Arm PEG-Azide(疊氮化物-炔烴點擊化學PEG水凝膠) - Supramolecular polymer gels with potential model-network structure, Polym. Chem., 2014, 5, 3018-3029, Text.

8-Arm PEG-Vinylsulfone and 8-Arm PEG-Amine(交聯PEG微球和水凝膠) - Long term culture of HL-1 cardiomyocytes in modular poly(ethylene glycol) microsphere-based scaffolds crosslinked in the phase separated state. Acta Biomater. 2012, 8(1): 31–40, Text.

8-Arm PEG-Vinyl Sulfone(PEG水凝膠和蛋白質交聯) - Nanogel surface coatings for improved single-molecule imaging substrates, J R Soc Interface. 2011 October 7; 8(63): 1400–1408, Text.

8-Arm PEG-Acrylate(PEG水凝膠) - Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration, Biomaterials, 2013(34): 7381-7388, Text.

8-Arm PEG-Maleimide(PEG水凝膠與硫醇活性蛋白的共軛) - Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels, Chem. Commun., 2014, 50, 8174-8176, Text. Experimental details in SI.

自組裝 - 聚乙二醇化脂質體，膠束，單層平面

DSPE-PEG-Maleimide(酶巰基修飾) - Matrix Metalloprotease 2-Responsive Multifunctional Liposomal Nanocarrier for Enhanced Tumor Targeting, ACS Nano, 2012, 6(4), pp 3491–3498, Text.

DSPE-PEG-Maleimide(肽巰基修飾) - APN/CD13-targeting as a strategy to alter the tumor accumulation of liposomes, Journal of Controlled Release 154(2011) 298–305, Text.

DSPE-PEG-MAL(自組裝和巰基修飾) - Vascular targeted single-walled carbon nanotubes for near-infrared light therapy of cancer, Nanotechnology 22(2011) 455101, Text.

DSPE-PEG-MAL(自組裝和巰基修飾) - Targeting single-walled carbon nanotubes for the treatment of breast cancer using photothermal therapy, 2013 Nanotechnology 24 375104, Text.

DSPE-PEG-MAL(聚乙二醇修飾膠束和巰基PEG修飾) - Aggregation-enhanced fluorescence in PEGylated phospholipid nanomicelles for in vivo imaging, Biomaterials 32(2011) 5880e5888, Text.

mPEG-DSPE(納米粒子膠束封裝) - Using 915 nm Laser Excited Tm3þ/ Er3þ/Ho3þ-Doped NaYbF4 Upconversion Nanoparticles for in Vitro and Deeper in Vivo Bioimaging without Overheating Irradiation, ACS Nano, 2011, 5(5), pp 3744–3757, Text.

mPEG-DSPE(脂溶性納米粒子的表面PEG修飾) - ‘Green’-synthesized near-infrared PbS quantum dots with silica–PEG dual-layer coating: ultrastable and biocompatible optical probes for in vivo animal imaging, 2012 Nanotechnology 23 245701, Text.

mPEG-DSPE(量子點膠束封裝) - Biocompatible and Photostable AIE Dots with Red Emission for In Vivo Two-Photon Bioimaging. Sci. Rep. 2014, 4, 4279, Text.

mPEG-DSPE(聚乙二醇化納米粒子磷脂膠束封裝) - Optimization of Optical Excitation of Upconversion Nanoparticles for Rapid Microscopy and Deeper Tissue Imaging with Higher Quantum Yield. Theranostics 2013, 3(5):306-316, Text.

mPEG-C18(膠束制劑與脂化核苷共組裝) - Lysosomal Delivery of a Lipophilic Gemcitabine Prodrug Using Novel Acid-Sensitive Micelles Improved Its Antitumor Activity, Bioconjugate Chem., 2012, 23(5), pp 966–980, Text.

C18-PEG-NHS(膠束封裝和肽胺PEG修飾) - Octreotide-Modified N-Octyl-O, N-Carboxymethyl Chitosan Micelles as Potential Carriers for Targeted Antitumor Drug Delivery. J Pharm Sci. 2012 Feb;101(2):627-40, Text.

C18-PEG6-Azide(PEGy修飾的膠束和蛋白質點擊化學的PEG修飾) - Evaluation of Nanolipoprotein Particles(NLPs) as an In Vivo Delivery Platform, PLoS ONE 9(3): e93342. doi:10.1371/journal.pone.0093342, Text.

mPEG-COOH(聚乙二醇表面活性劑，納米顆粒的封裝和肽的生物共軛) - Highly emissive PEG-encapsulated conjugated polymer nanoparticles, Nanoscale, 2012, 4, 5694, Text.

mPEG-Hydrazide(膠束的可逆PEG修飾) - Lysosomal Delivery of a Lipophilic Gemcitabine Prodrug Using Novel Acid-Sensitive Micelles Improved Its Antitumor Activity, Bioconjugate Chem., 2012, 23(5), pp 966–980, Text.

小分子聚乙二醇化及其他

mPEG-Amine(羧基PEG修飾) - A Photoinducible 1,3-Dipolar Cycloaddition Reaction for Rapid, Selective Modification of Tetrazole-Containing Proteins, Angew Chem Int Ed Engl. 2008;47(15):2832-5, Text, experimental details in SI.

Fmoc-NH-PEG-NHS - Polyelectrolyte Nanogels Decorated with Monoclonal Antibody for Targeted Drug Delivery, React Funct Polym. 2011 March 1; 71(3): 315–323) - &&, Text.

Fmoc-NH-PEG-NHS(生物素與小分子藥物的交聯) - A prodrug nanoassembly entrapping drugs as a tumor-targeted delivery system, Chem. Commun., 2013, 49, 801-803, Text.

mPEG-OH(光敏共聚物的共聚反應) - Soft Nanoparticles Assembled from Linear Poly(ethylene glycol) and Linear Brush Polydimethylsiloxane Diblock Copolymers, J. Polym. Sci. A Polym. Chem., 52: 1251–1262, Text.

mPEG-Amine(用于基因傳遞的PEG修飾的PEI共聚物) - Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA, Int J Pharm. 2012 May 1; 427(1): 123–133, Text.

4-Arm PEG-OH and 4-Arm PEG-PLA(二段共聚物和自組裝) - Biodegradable Polymersomes from Four-Arm PEG-b-PDLLA for Encapsulating Hemoglobin, J. APPL. POLYM. SCI. 2014, DOI: 10.1002/APP.40433, Text.

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